Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium hydride → ethyl 4-[(4-methoxybenzenesulfonyl)pyridin-3-ylmethylamino]-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 4-methoxy-N-(pyridin-3-ylmethyl)benzenesulfonamide | HCID 809740 | — |
| 반응물 | Ethyl 4-chloro-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate | HCID 3572813 | — |
| 생성물 | ethyl 4-[(4-methoxybenzenesulfonyl)pyridin-3-ylmethylamino]-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate | HCID 22322164 | — |
반응 단계
Following the procedure of Example 38, the product of Example 33 is reacted with (4-methoxybenzenesulfonyl)(3-pyridinylmethyl) amine and sodium hydride to provide ethyl 4-[(4-methoxybenzenesulfonyl)pyridin-3-ylmethylamino]-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate. m.p. 89°-91° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06946473B2 |
| 출처 데이터셋 | uspto-grants-2005_09 |
| ORD ID | ord-964d40d2f58f4cdaa8438954a748c13c |
| 출처 메모 | uspto-grants-2005_09 |