Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Bromoquinoline → 1-Methyl-4-(quinolin-3-yl)piperidin-4-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Bromoquinoline | HCID 21413 | — |
| 반응물 | 1-Methyl-4-piperidone | HCID 74049 | — |
| 반응물 | Butyllithium | HCID 178418339 | — |
| 용매 | Hexane | HCID 8058 | — |
| 생성물 | 1-Methyl-4-(quinolin-3-yl)piperidin-4-ol | HCID 19096203 | 53.84% |
반응 단계
95.01 g of 3-bromoquinoline were treated with 200 ml of a 2.5M solution of butyllithium in hexane and 51.62 g of 1-methylpiperid-4-one in accordance with the procedure described in Stage A of Example 1, in order to obtain the expected product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05242933 |
| 출처 데이터셋 | uspto-grants-1993_09 |
| ORD ID | ord-dbcee54bd5e04652bd5d90e8abadadc6 |
| 출처 메모 | uspto-grants-1993_09 |