Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → [5-(Methyl-propyl-amino)-2-nitro-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | N-Methylpropylamine | HCID 12315 | — |
| 반응물 | (5-Chloro-2-nitro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester | HCID 69489376 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 생성물 | [5-(Methyl-propyl-amino)-2-nitro-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester | HCID 69487144 | — |
반응 단계
The title compound was prepared from (5-chloro-2-nitro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example A1) (4.00 g, 11.7 mmol), N-methyl-propylamine (1.89 ml, 17.6 mmol) and triethylamine (5.73 ml, 41.1 mmol) in DMSO (30 mL) at RT according to the general procedure C. Obtained as a yellow solid (4.04 g, 91%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06949542B2 |
| 출처 데이터셋 | uspto-grants-2005_09 |
| ORD ID | ord-42a383073b2d4231bcc91bae77b0a395 |
| 출처 메모 | uspto-grants-2005_09 |