Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(2-Amino-5-cyclopropyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester → (5-Cyclopropyl-2-{3-[3-(2-methyl-pyridin-4-yl)-phenyl]-3-oxo-propionylamino}-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (2-Amino-5-cyclopropyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester | HCID 69489287 | — |
| 반응물 | 3-[3-(2-Methyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester | HCID 69489307 | — |
| 생성물 | (5-Cyclopropyl-2-{3-[3-(2-methyl-pyridin-4-yl)-phenyl]-3-oxo-propionylamino}-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester | HCID 86589449 | — |
반응 단계
The title compound was prepared (2-amino-5-cyclopropyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J39) (289 mg, 0.914 mmol) and 3-[3-(2-methyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K12) (284 mg, 0.914 mmol) according to the general procedure M. Obtained as a yellow foam (368 mg, 73%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06949542B2 |
| 출처 데이터셋 | uspto-grants-2005_09 |
| ORD ID | ord-620d5c9d1aa54da0a539bcf332991524 |
| 출처 메모 | uspto-grants-2005_09 |