Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(Phenylmethyl)-1H-indazol-5-amine → (1-benzyl-1H-indazol-5-yl)-(6-iodo-7-fluoroquinazolin-4-yl)-amine hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(Phenylmethyl)-1H-indazol-5-amine | HCID 212069 | — |
| 반응물 | 4-Chloro-7-fluoro-6-iodoquinazoline | HCID 21952006 | — |
| 생성물 | (1-benzyl-1H-indazol-5-yl)-(6-iodo-7-fluoroquinazolin-4-yl)-amine hydrochloride | HCID 21952244 | — |
반응 단계
Prepared according to Procedure A from 1-benzyl-1H-indazol-5-ylamine and 4-chloro-6-iodo-7-fluoroquinazoline. δH (400 MHz, DMSO-d6): 11.55(s, 1H), 9.41(d, 1H), 8.8(s, 1H), 8.18(s, 1H), 8.05(d, 1H), 7.78(d, 1H), 7.69(d, 1H), 7.61(m, 1H), 7.29(m, 2H), 7.23(m, 3H), 5.67(s, 2H). ESI-MS m/z 496(M+1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06713485B2 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-600142b03707499085fabf2c118b8b52 |
| 출처 메모 | uspto-grants-2004_03 |