참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 2-(Tributylstannyl)pyridine | HCID 607784 | — |
| 반응물 | tert-Butyl 3-iodobenzylcarbamate | HCID 11645663 | — |
| 촉매 | HCID 178418397 | HCID 178418397 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | Tert-butyl-3-(pyridin-2-yl)benzylcarbamate | HCID 69029928 | 78.1% |
반응 단계
To a solution of tert-butyl-3-iodobenzylcarbamate (166 mg, 0.50 mmol) in Dioxane (1.5 mL) was added Pd(PPh3)4 (58 mg, 0.05 mmol) and 2-(tributylstannyl)pyridine (275 mg, 0.75 mmol). After stirring at 100° C. for 2 h, it was concentrated and the residue was purified by column chromatography to give tert-butyl-3-(pyridin-2-yl)benzylcarbamate (111 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US09102625B2 |
|---|
| 출처 데이터셋 | uspto-grants-2015_08 |
|---|
| ORD ID | ord-e72f51f70e1d4e489c74252f62880107 |
|---|
| 출처 메모 | uspto-grants-2015_08 |
|---|
