Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylformamide dimethyl acetal → 1-(3,4-Difluorophenyl)-3-(dimethylamino)prop-2-en-1-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| 반응물 | 1-(3,4-Difluorophenyl)ethan-1-one | HCID 123052 | — |
| 생성물 | 1-(3,4-Difluorophenyl)-3-(dimethylamino)prop-2-en-1-one | HCID 63706116 | 84% |
반응 단계
The title compound was prepared in 84% yield from 1-(3,4-difluorophenyl)ethanone and DMF-DMA according to the procedure for the preparation of Example 12, part A. 1H NMR (400 MHz, CDCl3): δ 2.93 (3H, s), 3.16 (3H, s), 5.62 (1H, d, J=12.0 Hz), 7.13-7.20 (1H, m), 7.63-7.76 (2H, m), 7.83 (1H, d, J=12.0 Hz).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09107916B2 |
| 출처 데이터셋 | uspto-grants-2015_08 |
| ORD ID | ord-8e532665e6fd4c858cd1d1d1e231ffbc |
| 출처 메모 | uspto-grants-2015_08 |