Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → HCID 10270267, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | Ethyl Acetate | HCID 8857 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | [2-Fluoro-4-(2,2,4,4-tetramethyl-chroman-6-ylethynyl) phenyl]acetic acid ethyl ester | HCID 69548829 | — |
| 용매 | Hexane | HCID 8058 | — |
| 생성물 | HCID 10270267 | HCID 10270267 | — |
반응 단계
Following general procedure L and using [2-fluoro-4-(2,2,4,4-tetramethyl-chroman-6-ylethynyl)phenyl] acetic acid ethyl ester (Compound 31, 0.21 g, 0.58 mmol), 5 mL of methanol and 1M sodium hydroxide solution (2 mL) followed by flash column chromatography over silica gel (230-400 mesh) using 50% ethyl acetate in hexane, the title compound was obtained as a solid (0.184 g, 93%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06713647B2 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-83d28b629bb744e3b3f7dee488eac008 |
| 출처 메모 | uspto-grants-2004_03 |