Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Mercaptoethanol → N-[4-(4-Piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-4-(2-hydroxyethylthio)butyramide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Mercaptoethanol | HCID 1567 | — |
| 반응물 | N-[4-(4-piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-4-chlorobutyramide | HCID 67726214 | — |
| 생성물 | N-[4-(4-Piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-4-(2-hydroxyethylthio)butyramide | HCID 67725591 | 66% |
반응 단계
Following a procedure similar to that described in Example 1, but using N-[4-(4-piperidinomethyl-2-pyridyloxy) -cis-2-butenyl]-4-chlorobutyramide (prepared as described in Preparation 2) and 2-mercaptoethanol as starting materials, in relative proportions similar to those used in that Example, and carrying out the reaction at 80° C. for 5 hours, the title compound was obtained in a 66% yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05616579 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-d2b2d96dd1ab4d00b20e980386f6c29d |
| 출처 메모 | uspto-grants-1997_04 |