Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Methylbenzyl isocyanate → 1-Cyclopentyl-7-methoxy-3-(3-methyl-benzyl)-1H-pyrimido[5,4-c]quinoline-2,4-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Methylbenzyl isocyanate | HCID 2733387 | — |
| 반응물 | 4-Cyclopentylamino-8-methoxy-quinoline-3-carboxylic acid ethyl ester | HCID 67249718 | — |
| 생성물 | 1-Cyclopentyl-7-methoxy-3-(3-methyl-benzyl)-1H-pyrimido[5,4-c]quinoline-2,4-dione | HCID 58329419 | 43.3% |
반응 단계
1-Cyclopentyl-7-methoxy-3-(3-methyl-benzyl)-1H-pyrimido[5,4-c]quinoline-2,4-dione (18 mg) was prepared from 4-cyclopentylamino-8-methoxy-quinoline-3-carboxylic acid ethyl ester (0.1 mmol) and 1-isocyanatomethyl-3-methyl-benzene (0.5 mmol) following general procedure C. LCMS: m/z 416 [M+1]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08853226B2 |
| 출처 데이터셋 | uspto-grants-2014_10 |
| ORD ID | ord-5c602c2b83f4432ba371a39acdeeecd1 |
| 출처 메모 | uspto-grants-2014_10 |