Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Azobisisobutyronitrile → Methyl 4'-(bromomethyl)biphenyl-2-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Azobisisobutyronitrile | HCID 6547 | — |
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 반응물 | (1,1'-Biphenyl)-2-carboxylic acid, 4'-methyl-, methyl ester | HCID 1393873 | — |
| 촉매 | Azobisisobutyronitrile | HCID 6547 | — |
| 용매 | Carbon Tetrachloride | HCID 5943 | — |
| 생성물 | Methyl 4'-(bromomethyl)biphenyl-2-carboxylate | HCID 11012181 | 59.6% |
반응 단계
2.0 g (8.8 mmol) of methyl 2-(4'-methylphenyl)benzoate, 1.6 g (9.0 mmol) of N-bromosuccinimide and 0.05 g of α,α'-azobis(isobutyronitrile) [another name; 2,2'-azobis(isobutyronitrile)] were dissolved in carbon tetrachloride (110 ml), followed by heating under reflux for 2 hours. The resultant mixture was filtered to remove insolubles, and then vacuum concentration was effected. The residue was recrystallized from a n-hexane/isopropyl ether mixed solvent to give 1.6 g of the title compound (yield; 59%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05618969 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-11522c2bf8264c559cda5831527097e2 |
| 출처 메모 | uspto-grants-1997_04 |