Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Chloronicotinoyl chloride → N-(2-bromo-6-methoxy-4-methyl-3-pyridinyl)-2-chloro-3-pyridinecarboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Chloronicotinoyl chloride | HCID 2774541 | — |
| 반응물 | 2-Bromo-6-methoxy-4-methylpyridin-3-amine | HCID 19960055 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | N-(2-bromo-6-methoxy-4-methyl-3-pyridinyl)-2-chloro-3-pyridinecarboxamide | HCID 19960021 | 84.6% |
반응 단계
2-Chloronicotinoyl chloride (3.5 g) was added to a solution of 3-amino-2-bromo-6-methoxy-4-methylpyridine (4.5 g) in methylene chloride, and the resulting mixture was stirred overnight at room temperature, and triturated with diisopropyl ether. The precipitated solid was filtered to give 6.0 g of the title compound, suitable for use in the next reaction.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05620974 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-6a0646106c7b4305a06b3cf1bf22313a |
| 출처 메모 | uspto-grants-1997_04 |