Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Amino-4-methyl-3-nitropyridine → 4-Methylpyridine-2,3-diamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Amino-4-methyl-3-nitropyridine | HCID 243166 | — |
| 촉매 | Nickel | HCID 935 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 4-Methylpyridine-2,3-diamine | HCID 317495 | 100.1% |
반응 단계
A mixture of 2-amino-4-methyl-3-nitropyridine (919 mg, 6.0 mmol), ethanol (20 mL) and Raney Ni (about 200 mg) was shaken under H2 (30-40 psi) for 1 h, then filtered. The filtrate was evaporated to dryness, giving 740 mg (100%) of the diamine 56, mp 114°-5° C. 1H NMR (DMSO-d6), 1.997 (s, 3H), 4.359 (s, 2H), 5.250 (s, 2H), 6.264 (d, 1H, J=3), 7.173 (d, 1H, J=3).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05620978 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-972228a99c6b4092b37618fa57402f8d |
| 출처 메모 | uspto-grants-1997_04 |