Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Anhydride → 4'-Bromo-2'-(trifluoromethyl)acetanilide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 반응물 | 4-Bromo-2-(trifluoromethyl)aniline | HCID 67960 | — |
| 생성물 | 4'-Bromo-2'-(trifluoromethyl)acetanilide | HCID 2773417 | 99.7% |
반응 단계
A solution of 2-amino-5-bromobenzotrifluoride (1.623 g, 6.76 mmol, Aldrich) in acetic anhydride (10 mL) was stirred at room temperature for 12 h to produce a white needle precipitate. It was filtered to give 1.840 g (99.7%) of title compound. Mp: 140°-2° C., 1HNMR (CDCl3): δ 2.212 (s, 3H); 7.358 (s, 1H); 7.659 (d, 1H, J =8.7 Hz); 7.726 (d, 1H, J=1.8 Hz); 8.118 (d, 1H, J=8.4 Hz).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05620979 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-a8f3fd9bf59a4c7c9c40d591d3b3323c |
| 출처 메모 | uspto-grants-1997_04 |