Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-[4-Chloro-2-nitro-5-(trifluoromethyl)phenyl]acetamide → 4-Chloro-2-nitro-5-(trifluoromethyl)aniline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-[4-Chloro-2-nitro-5-(trifluoromethyl)phenyl]acetamide | HCID 22318004 | — |
| 용매 | Hydrochloric Acid | HCID 313 | — |
| 생성물 | 4-Chloro-2-nitro-5-(trifluoromethyl)aniline | HCID 2737645 | 78% |
반응 단계
A mixture of 3-acetamido-6-chloro-4-nitrobenzotrifluoride (780 mg, 2.76 mmol) in concentrated HCl (3 mL) was refluxed overnight and it was extracted by ethyl acetate (2×3 mL). The extract was dried over Mg2SO4 and evaporated to give 517 mg (78% ) of 3-amino-6-chloro-4-nitrobenzotrifluoride. 1H NMR (CDCl3): δ 6.205 (S, 2H); 7.206 (s, 1H); 8.263 (s, 1H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05620979 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-971afb0efd3a4d0d94a318d0837f4da0 |
| 출처 메모 | uspto-grants-1997_04 |