Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
p-Chlorophenacyl bromide → 2-Amino-4-(4-chlorophenacyl)-1-(2-morpholinoethyl)benzimidazolium bromide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | p-Chlorophenacyl bromide | HCID 68303 | — |
| 반응물 | 1-(2-Morpholin-4-ylethyl)-2-aminobenzimidazole | HCID 568011 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 2-Amino-4-(4-chlorophenacyl)-1-(2-morpholinoethyl)benzimidazolium bromide | HCID 67711814 | 95% |
반응 단계
A solution of 2.33 g (10 mmol) of 4-chlorophenacyl bromide in 25 ml of acetone is added to a hot solution of 2-amino-1-(2-morpholinoethyl)benzimidazole (2.46 g, 10 mmol) in 75 ml of acetone. The mixture is stirred, heated at the boil for 5 minutes and maintained at room temperature. Three hours later a precipitate of the title compound appears, which is filtered and washed with acetone and with ether.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05623073 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-aaf1ce63975b4e8fb7fd87ea52561c4b |
| 출처 메모 | uspto-grants-1997_04 |