Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Butanaminium, N,N,N-tributyl-, azide → Ethanethioic acid S-[5-(azidomethyl)tetrahydro-3-thienyl]ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Butanaminium, N,N,N-tributyl-, azide | HCID 5743232 | — |
| 반응물 | Ethanethioic acid S-[tetrahydro-5-(iodomethyl)-3-thienyl]ester | HCID 54241013 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | Ethanethioic acid S-[5-(azidomethyl)tetrahydro-3-thienyl]ester | HCID 54464306 | 46.4% |
반응 단계
A solution, under argon, of 0.183 g of product from Example 140 in 1.0 ml of dry methylene chloride is treated with 0.689 g of tetra-n-butyl-ammonium azide. The reaction mixture is stirred vigorously overnight at room temperature. The reaction is concentrated in vacuo and the residue purified by chromatography (silica gel: 0-10% diethyl ether/hexane) to give 0.061 g of the desired product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05623081 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-898193f0f65f4694bd51481f91ebc822 |
| 출처 메모 | uspto-grants-1997_04 |