Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(1-Chloropropyl)benzene → (2R)-2-({2-Amino-5-[(1-phenylpropyl)thio][1,3]thiazolo[4,5-d]pyrimidin-7-yl}amino)-4-methylpentan-1-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (1-Chloropropyl)benzene | HCID 524241 | — |
| 반응물 | HCID 178445911 | HCID 178445911 | — |
| 생성물 | (2R)-2-({2-Amino-5-[(1-phenylpropyl)thio][1,3]thiazolo[4,5-d]pyrimidin-7-yl}amino)-4-methylpentan-1-ol | HCID 11842649 | 31% |
반응 단계
The title compound was synthesized as a mixture of two diastereomers by general method A from the reaction of (2R)-2-[(2-amino-5-mercapto[1,3]thiazolo[4,5-d]pyrimidin-7-yl)amino]-4-methylpentan-1-ol (30 mg, 100 μmol) with (1-chloropropyl)benzene (15.5 μL, 100 μmol) to give 13 mg (31% yield) as an oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07947693B2 |
| 출처 데이터셋 | uspto-grants-2011_05 |
| ORD ID | ord-f3b191c93dd14989bc7303a4745678f1 |
| 출처 메모 | uspto-grants-2011_05 |