Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,4-Dichlorobenzylamine → Gsk1370319A
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,4-Dichlorobenzylamine | HCID 1485 | — |
| 반응물 | (4-Fluoro-2-(trifluoromethyl)phenyl)methanamine | HCID 2734878 | — |
| 반응물 | N-{[4-fluoro-2-(trifluoromethyl)phenyl]methyl}-1-methyl-5-oxoprolinamide | HCID 67458706 | — |
| 생성물 | Gsk1370319A | HCID 67461788 | — |
반응 단계
N-[(2,4-dichlorophenyl)methyl]-1-methyl-5-oxoprolinamide was prepared in a manner analogous to that described above for the synthesis of N-{[4-fluoro-2-(trifluoromethyl)phenyl]methyl}-1-methyl-5-oxoprolinamide (Example 83) but [(2,4-dichlorophenyl)methyl]amine was substituted for {[4-fluoro-2-(trifluoromethyl)phenyl]methyl}amine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08048907B2 |
| 출처 데이터셋 | uspto-grants-2011_11 |
| ORD ID | ord-dea8d8dbf8a446459a5e322827833688 |
| 출처 메모 | uspto-grants-2011_11 |