Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 2,4,6-Tris(bromomethyl)nitrobenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | 1,3,5-Tris(bromomethyl)benzene | HCID 530258 | — |
| 반응물 | Nitronium tetrafluoroborate | HCID 11073463 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 2,4,6-Tris(bromomethyl)nitrobenzene | HCID 14959170 | 86.4% |
반응 단계
To a solution of 5 g (0.014 mole) of the tribromide 8 in 100 ml of CH3CN was added, at room temperature and under argon atmosphere, in a dropwise fashion 3.72 g (0.028 mole) of nitronium tetrafluoroborate in 200 ml of CH3CN. The solution was then stirred for 20 minutes longer, poured into water and the mixture extracted with CH2Cl2. The CH2Cl2 extracts were washed with 10% NaHCO3, dried (Na2SO4) and solvents removed to afford 4.86 g (86%) of the desired nitro compound 27: NMR (CDCl3) 4.5 (s,6,--CH2Br), 7.55 (s,--C6H2).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05245038 |
| 출처 데이터셋 | uspto-grants-1993_09 |
| ORD ID | ord-728658d230cb49b7815fa4f092792817 |
| 출처 메모 | uspto-grants-1993_09 |