Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-carboxylic acid → 2,2-Dimethyl-2,3-dihydro-benzofuran-7-carboxylic acid[(1s,2s,5r)-3-(2-methyl-5-m-tolyl-thiazole-4-carbonyl)-3-aza-bicyclo[3.1.0]hex-2-ylmethyl]-amide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-carboxylic acid | HCID 2795469 | — |
| 반응물 | ((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanone | HCID 66998654 | — |
| 생성물 | 2,2-Dimethyl-2,3-dihydro-benzofuran-7-carboxylic acid[(1s,2s,5r)-3-(2-methyl-5-m-tolyl-thiazole-4-carbonyl)-3-aza-bicyclo[3.1.0]hex-2-ylmethyl]-amide | HCID 25183718 | — |
반응 단계
prepared by reaction of ((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanone with 2,2-Dimethyl-2,3-dihydro-benzofuran-7-carboxylic acid. LC-MS (basic): tR=0.97 min; [M+H]+=502.4.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08063099B2 |
| 출처 데이터셋 | uspto-grants-2011_11 |
| ORD ID | ord-50d6528798614828b472b6266776714c |
| 출처 메모 | uspto-grants-2011_11 |