Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3,4-Dimethylbenzoic acid → 1-(3,4-Dimethylbenzoyl)-2-methyl-1,2,3,4-tetrahydro-4-quinolinol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3,4-Dimethylbenzoic acid | HCID 12073 | — |
| 반응물 | 1,2,3,4-Tetrahydro-2-methyl-4-quinolinol | HCID 147634 | — |
| 생성물 | 1-(3,4-Dimethylbenzoyl)-2-methyl-1,2,3,4-tetrahydro-4-quinolinol | HCID 22339291 | 62.5% |
반응 단계
Starting with 2-methyl-1,2,3,4-tetrahydro-4-quinolinol (1.00 g, 6.12 mmol) synthesized in the published manner and 3,4-dimethylbenzoic acid (1.20 g, 7.96 mmol), the same procedure as shown in Reference Example 19 was repeated to give the titled compound (1.13 g, yield: 48%) as an oil. (cis:trans=1:1)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06930104B2 |
| 출처 데이터셋 | uspto-grants-2005_08 |
| ORD ID | ord-b438aaa24d5e473fab42bdf6165d050d |
| 출처 메모 | uspto-grants-2005_08 |