Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sulfuric Acid → 5-((2,2,2-Trifluoroacetamido)methyl)-2-chloro-4-methoxybenzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | 2,2,2-Trifluoro-N-(hydroxymethyl)acetamide | HCID 3084931 | — |
| 반응물 | 2-Chloro-4-methoxybenzoic acid | HCID 12648026 | — |
| 생성물 | 5-((2,2,2-Trifluoroacetamido)methyl)-2-chloro-4-methoxybenzoic acid | HCID 90019421 | 39.9% |
반응 단계
The title compound was prepared according to the procedure described in step-1 of Intermediate-26 by using 2-chloro-4-methoxybenzoic acid (0.060 g), 2,2,2-trifluoro-N-(hydroxymethyl)acetamide (0.050 g) and H2SO4 (2 mL) to afford 0.040 g of the desired product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09439890B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-28def1e1d84f42db8ac98d0a93fae888 |
| 출처 메모 | uspto-grants-2016_09 |