Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sulfuric Acid → N-(5-amino-4-chloro-2-fluorobenzyl)-2,2,2-trifluoroacetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | Sodium Azide | HCID 33557 | — |
| 반응물 | 5-((2,2,2-Trifluoroacetamido)methyl)-2-chloro-4-fluorobenzoic acid | HCID 89736668 | — |
| 생성물 | N-(5-amino-4-chloro-2-fluorobenzyl)-2,2,2-trifluoroacetamide | HCID 90018998 | 64,668.398% |
반응 단계
The title compound was prepared according to the procedure described in step-1 of Intermediate-57 by using 5-((2,2,2-trifluoroacetamido)methyl)-2-chloro-4-fluorobenzoic acid (3.0 g), conc. H2SO4 and sodium azide (0.793 g, 0.012 mmol) to afford 2.1 g of the desired product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09439890B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-069b0936d7534524b20bdb7e804dfc9b |
| 출처 메모 | uspto-grants-2016_09 |