Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylformamide → Dimethyl 2,2'-dithiobisbenzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | Dithiodibenzoic acid | HCID 8409 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 용매 | Methanol | HCID 887 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 용매 | Thionyl Chloride | HCID 24386 | — |
| 생성물 | Dimethyl 2,2'-dithiobisbenzoate | HCID 79574 | 50% |
반응 단계
25 g (81.6 mmol) of dithiodibenzoic acid is refluxed in 60 ml of SOCl2 and 1.5 ml of dimethylformamide (DMF) for 3 hrs. Then the excess of SOCl2 is distilled off, and the residue is dissolved in CHCl3 and added dropwise to a solution of methanol (50 ml) and triethylamine (0.204 mol) in CHCl3 (300 l). After standing over night the reaction mixture is shaked with water and saturated K2CO3 solution. After drying the organic layer the solvent is evaporated and methanol is added to the residue (oil). 13.6 g (50%) of solid product is obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07901867B2 |
| 출처 데이터셋 | uspto-grants-2011_03 |
| ORD ID | ord-cad53b8c9b884337997cc19785bc4fe7 |
| 출처 메모 | uspto-grants-2011_03 |