Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 601264생성일: 2026년 10월 24일
3-Methylcyclohexanone → 6-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-7-hydroxy-4-{[3-methylcyclohexylidene]amino}thieno[3,2-b]pyridin-5(4H)-one
https://huagongshe.com/ko/reaction/601264
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 3-Methylcyclohexanone | HCID 11567 | — |
| 반응물 | 4-amino-6-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-7-hydroxythieno[3,2-b]pyridin-5(4H)-one | HCID 136373627 | — |
| 용매 | Dimethylacetamide | HCID 31374 | — |
| 생성물 | 6-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-7-hydroxy-4-{[3-methylcyclohexylidene]amino}thieno[3,2-b]pyridin-5(4H)-one | HCID 136358481 | — |
반응 단계
The product of Example 268D (0.054 g, 0.15 mmol) was reacted with 3-methylcyclohexanone (1.26 g, 11.25 mmol) in N,N-dimethylacetamide (1 mL) in a sealed tube at 135° C. for 45 minutes in a microwave reactor. The reaction was cooled to 25° C. and concentrated under vacuum. The resulting residue was triturated with diethyl ether (3 mL) and filtered to give the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US07902203B2 |
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| 출처 데이터셋 | uspto-grants-2011_03 |
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| ORD ID | ord-e4632e7690844eb6b4e6e8f796767630 |
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| 출처 메모 | uspto-grants-2011_03 |
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