Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4'-Hydroxyacetophenone → 4-acetylphenyl 2,3,4-tri-O-acetyl-5-thio-beta-D-xylopyranoside
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4'-Hydroxyacetophenone | HCID 7469 | — |
| 반응물 | 2,3,4-tri-O-acetyl-5-thio-alpha-xylopyranosyl bromide | HCID 10926314 | — |
| 촉매 | Zincchloride | HCID 3007855 | — |
| 촉매 | Silver imidazolate | HCID 10931941 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 4-acetylphenyl 2,3,4-tri-O-acetyl-5-thio-beta-D-xylopyranoside | HCID 15067850 | 18% |
반응 단계
If the procedure described in Preparation LXXXIII is followed starting from 2 g (14.7.10-3 mol) of 1-(4-hydroxyphenyl)ethanone, 2.8 g (16.10-3 mol) of silver imidazolate, 5.74 g (16.1.10-3 mol) of 2,3,4-tri-O-acetyl-5-thio-α-D-xylopyranosyl bromide and 4 g (29.3.10-3 mol) of zinc chloride in 100 ml of methylene chloride, 0.96 g (yield: 18%) of the expected product is obtained after purification by chromatography on silica gel using a toluene/ethyl acetate mixture (6/1 v/v) as the eluent.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05246961 |
| 출처 데이터셋 | uspto-grants-1993_09 |
| ORD ID | ord-2e92d2415ae14a2c94e457a5f31e7891 |
| 출처 메모 | uspto-grants-1993_09 |