Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Cyanophenol → 3-cyanophenyl 2,3,4-tri-O-acetyl-5-thio-beta-D-xylopyranoside
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Cyanophenol | HCID 13394 | — |
| 반응물 | 2,3,4-Tri-o-acetyl-5-thioxylopyranosyl bromide | HCID 11382683 | — |
| 촉매 | Zinc Oxide | HCID 3007857 | — |
| 용매 | Toluene | HCID 1140 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 3-cyanophenyl 2,3,4-tri-O-acetyl-5-thio-beta-D-xylopyranoside | HCID 15067856 | 25% |
반응 단계
If the procedure described in Preparation LXXVIII is followed starting from 0.5 g (1.4.10-3 mol) of 2,3,4-tri-O-acetyl-5-thio-D-xylopyranosyl bromide, 0.25 g (2.1.10-3 mol) of 3-hydroxybenzonitrile and 170 mg (2.1.10-3 mol) of zinc oxide (ZnO) in 4 ml of anhydrous toluene and 4 ml of acetonitrile, 138 mg (yield: 25%) of the expected product are obtained after purification by chromatography on silica gel using a hexane/ethyl acetate mixture (2/1 v/v) as the eluent, and precipitation in ether.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05246961 |
| 출처 데이터셋 | uspto-grants-1993_09 |
| ORD ID | ord-de6b93c29d3a4007a7f8a9a45c1c7379 |
| 출처 메모 | uspto-grants-1993_09 |