Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phosphorus tribromide → 1-Bromo-4-(1-bromoethyl)benzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phosphorus tribromide | HCID 24614 | — |
| 반응물 | 1-(4-Bromophenyl)ethanol | HCID 95352 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 1-Bromo-4-(1-bromoethyl)benzene | HCID 9838146 | 75% |
반응 단계
A solution of 1-(4-bromo-phenyl)-ethanol (4.21 g, 20.9 mmol) in 15 mL of CH2Cl2 was reacted with 15 mL of 1.0M PBr3 in CH2Cl2 at room temperature for 4 h. Quenched by pouring into ice and adjusted to pH 9 with 5% aqueous NaHCO3. Extracted with CH2Cl2 and dried over Na2SO4, filtered and concentrated under vacuum giving the title compound (4.1 g, 75%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07915411B2 |
| 출처 데이터셋 | uspto-grants-2011_03 |
| ORD ID | ord-a05d650c55e340159ff537fcf554041f |
| 출처 메모 | uspto-grants-2011_03 |