Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-(Methylamino)propane-1,2-diol → N-[{3-[(2,3-dihydroxypropyl)(methyl)amino]propyl}(oxido)phenyl--sulfanylidene]-5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)nicotinamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-(Methylamino)propane-1,2-diol | HCID 2734122 | — |
| 반응물 | N-[(3-bromopropyl)(oxido)phenyl--sulfanylidene]-5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)nicotinamide | HCID 76585264 | — |
| 생성물 | N-[{3-[(2,3-dihydroxypropyl)(methyl)amino]propyl}(oxido)phenyl--sulfanylidene]-5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)nicotinamide | HCID 76585224 | — |
반응 단계
In a manner similar to that described for Example 508, N-[(3-bromopropyl)(oxido)phenyl--sulfanylidene]-5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)nicotinamide and 3-methylamino-1,2-propanediol were converted to the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07915443B2 |
| 출처 데이터셋 | uspto-grants-2011_03 |
| ORD ID | ord-51f9e9b8266c43e494d304aa85b158cc |
| 출처 메모 | uspto-grants-2011_03 |