Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thiomorpholine 1,1-dioxide → (S)-N-{[3-(1,1-dioxidothiomorpholin-4-yl)propyl](oxido)phenyl--sulfanylidene}-5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)nicotinamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thiomorpholine 1,1-dioxide | HCID 6484228 | — |
| 반응물 | N-[(3-bromopropyl)(oxido)phenyl--sulfanylidene]-5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)nicotinamide | HCID 76585264 | — |
| 생성물 | (S)-N-{[3-(1,1-dioxidothiomorpholin-4-yl)propyl](oxido)phenyl--sulfanylidene}-5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)nicotinamide | HCID 57657888 | — |
반응 단계
In a manner similar to that described for Example 508, N-[(3-bromopropyl)(oxido)phenyl--sulfanylidene]-5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)nicotinamide and thiomorpholine-1,1-dioxide were converted to the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07915443B2 |
| 출처 데이터셋 | uspto-grants-2011_03 |
| ORD ID | ord-99f8ef1589184e79bd08e12e9a53808f |
| 출처 메모 | uspto-grants-2011_03 |