Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cyclopentylhydrazine hydrochloride → HCID 10545058, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cyclopentylhydrazine hydrochloride | HCID 212349 | — |
| 반응물 | HCID 10541431 | HCID 10541431 | — |
| 반응물 | Sodium Methoxide | HCID 10942334 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | HCID 10545058 | HCID 10545058 | — |
반응 단계
A stirred mixture of 3-methoxy-1-(3-methoxyphenyl)-2-oxo-4-propionyl-1,2,5,6-tetrahydro-pyridine (0.49 grams, 1.7 mmole), cyclopentylhydrazine hydrochloride (0.40 grams) and sodium methoxide (46 mg, 0.85 mmole) in anhydrous ethanol was heated to reflux. After 16 hours, the mixture was concentrated under reduced pressure and chromatographed on a silica gel column using 1:4 ethyl acetate/hexane as eluent to give a white solid. Recrystallization from ether gave white needles. M.P. 64.65° C.; MS m/z [M+] 340.2025; HRMS [M+] 340.2046.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06004974 |
| 출처 데이터셋 | uspto-grants-1999_12 |
| ORD ID | ord-6d77ae71d4524779bbe1745cc5b103ac |
| 출처 메모 | uspto-grants-1999_12 |