Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium borohydride → [1-(1,2-Dimethyl-propyl)-4-methyl-cyclohex-3-enyl]-methanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium borohydride | HCID 4311764 | — |
| 반응물 | 1-(1,2-Dimethyl-propyl)-4-methyl-cyclohex-3-enecarbaldehyde | HCID 89705176 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | [1-(1,2-Dimethyl-propyl)-4-methyl-cyclohex-3-enyl]-methanol | HCID 89705124 | 87.3% |
반응 단계
1-(1,2-Dimethyl-propyl)-4-methyl-cyclohex-3-enecarbaldehyde (415 g) and methanol (300 mL) were charged into a reaction flask. Sodium borohydride (15 g) was added slowly and the temperature was kept at 35° C. with an ice bath. The reaction mixture was aged for 2 hours and quenched onto HCl (42 g) and ice and extracted with toluene. The reaction mixture was washed until neutral. The rushed over material provided the recovery of [1-(1,2-dimethyl-propyl)-4-methyl-cyclohex-3-enyl]methanol (366 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09441185B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-71b3a8faa9a24e578b96d0a231b93669 |
| 출처 메모 | uspto-grants-2016_09 |