Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Propynamide → 5,6-Dihydro-5-oxopyrazolo[1,5-c]quinazoline-2-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Propynamide | HCID 101445 | — |
| 반응물 | (3Z)-3-diazo-1H-indol-2-one | HCID 136455454 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | 5,6-Dihydro-5-oxopyrazolo[1,5-c]quinazoline-2-carboxamide | HCID 135735615 | 13.1% |
반응 단계
4.8 g (0.03 mole) of 3-diazooxindole and 2.4 g (0.035 mole) of the propiolamide are taken up in benzene (250 ml) and refluxed overnight under a stream of nitrogen. The light tan precipitates that form are filtered off and dried in a vacuum oven for 4 hours. Yield: 4.4 g. Additional refluxing of the filtrate gives 900 mg of product. Total yield: 5.3 g (77.4%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04145420 |
| 출처 데이터셋 | uspto-grants-1979_03 |
| ORD ID | ord-8f14655529db4b009c8a3304b7cd41c5 |
| 출처 메모 | uspto-grants-1979_03 |