Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
[[o-(Allyloxy)phenoxy]methyl]oxirane → 1-[3-(o-Allyloxy-phenoxy)-2-hydroxypropyl]-4-(2-oxo-hexahydro-1-pyrimidinyl)piperidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | [[o-(Allyloxy)phenoxy]methyl]oxirane | HCID 5743337 | — |
| 반응물 | 1-(Piperidin-4-yl)-1,3-diazinan-2-one | HCID 15572666 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 1-[3-(o-Allyloxy-phenoxy)-2-hydroxypropyl]-4-(2-oxo-hexahydro-1-pyrimidinyl)piperidine | HCID 20368036 | — |
반응 단계
A solution of 10.3 g of 1-(o-allyloxy-phenoxy)-2,3-epoxy-propane and 9.15 g of 1-(4-piperidyl)-2-oxo-hexahydropyrimidine in 7 ml abs. ethanol is heated for 5 hours to 95° C and then evaporated in vacuo. The residue is recrystallised from isopropanol to yield the 1-[3-(o-allyloxy-phenoxy)-2-hydroxypropyl]-4-(2-oxo-hexahydro-1-pyrimidinyl)-piperidine, which melts at 122°-125° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04075208 |
| 출처 데이터셋 | uspto-grants-1978_02 |
| ORD ID | ord-78a02935df9f4be98813576cff7f00fe |
| 출처 메모 | uspto-grants-1978_02 |