Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-[3-(2-Pyrazinecarbonylamino)propylthio]pyridine → 4-[3-(2-Pyrazinecarbonylamino)propylthio]pyridine dihydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-[3-(2-Pyrazinecarbonylamino)propylthio]pyridine | HCID 15231502 | — |
| 반응물 | Hydrochloride methanol | HCID 21893726 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 4-[3-(2-Pyrazinecarbonylamino)propylthio]pyridine dihydrochloride | HCID 19079163 | 85.6% |
반응 단계
To a solution of 704.5 mg (2.57 mmol) of 4-[3-(2-pyrazinecarbonylamino)propylthio]pyridine in 30 ml of methanol, 70 ml of 10% hydrochloric acid-methanol was added, and the mixture was stirred at room temperature for 2 hours. The solvent was distilled off and the residue was purified by recrystallization (solvent: ethanol-ether) to give 842.4 mg of the desired compound (85.6% yield, pale yellow crystals).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05246948 |
| 출처 데이터셋 | uspto-grants-1993_09 |
| ORD ID | ord-7c0a9d74a2794bf09aa140d9698f4f5f |
| 출처 메모 | uspto-grants-1993_09 |