Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,2-bis[N-[4-(4-pyridylthio)butyl]-N-propionylamino]benzene → 1,2-bis[N-[4-(4-pyridylthio)butyl]-N-propionylamino]benzene dihydrochlorid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,2-bis[N-[4-(4-pyridylthio)butyl]-N-propionylamino]benzene | HCID 19079128 | — |
| 반응물 | Hydrochloride methanol | HCID 21893726 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 1,2-bis[N-[4-(4-pyridylthio)butyl]-N-propionylamino]benzene dihydrochlorid | HCID 19079229 | 74.1% |
반응 단계
To a solution of 840 mg (1.53 mmol) of 1,2-bis[N-[4-(4-pyridylthio)butyl]-N-propionylamino]benzene in 20 ml of methanol, 80 ml of 10% hydrochloric acid/methanol was added, and the mixture was stirred for 30 minutes. The solvent was distilled off and the residue was recrystallized from ethanol/ether to give 707 mg of the desired product (74.1% yield, pale yellow crystals).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05246948 |
| 출처 데이터셋 | uspto-grants-1993_09 |
| ORD ID | ord-84de096b7dbe4838b438dd20613401fa |
| 출처 메모 | uspto-grants-1993_09 |