Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl 5-bromo-6-(cyclopropylmethoxy)picolinate → 6-Cyclopropylmethoxy-5-(6-oxa-1-aza-spiro[3.3]hept-1-yl)-pyridine-2-carboxylic acid methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl 5-bromo-6-(cyclopropylmethoxy)picolinate | HCID 71087286 | — |
| 반응물 | 6-Oxa-1-azaspiro[3.3]heptane oxalate | HCID 71303992 | — |
| 생성물 | 6-Cyclopropylmethoxy-5-(6-oxa-1-aza-spiro[3.3]hept-1-yl)-pyridine-2-carboxylic acid methyl ester | HCID 71087484 | — |
반응 단계
The title compound was synthesized in analogy to the procedure described in Example 32 a), using 5-bromo-6-(cyclopropylmethoxy)-pyridine-2-carboxylic acid methyl ester (Example 9 d) and 6-oxa-1-azaspiro[3.3]heptane, oxalate salt (CAN 1359655-43-8) as starting materials. MS (EI): m/e=305.0 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09321727B2 |
| 출처 데이터셋 | uspto-grants-2016_04 |
| ORD ID | ord-721af8dd044f448996a2a915dc991dce |
| 출처 메모 | uspto-grants-2016_04 |