Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → 5-Ethynyl-6-methylpyridin-2-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 6-Methyl-5-trimethylsilanylethynyl-pyridin-2-ylamine | HCID 59255232 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 5-Ethynyl-6-methylpyridin-2-amine | HCID 55285938 | — |
반응 단계
The title compound is synthesized according to general procedure GP3 starting from 4.3 g (21.0 mmol) 6-methyl-5-trimethylsilanylethynyl-pyridin-2-ylamine and 1.5 g (10.5 mmol) K2CO3 in 30 mL MeOH. The product is purified by chromatography on silica gel using a DCM/MeOH gradient. Yield: 3.6 g.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09321771B2 |
| 출처 데이터셋 | uspto-grants-2016_04 |
| ORD ID | ord-16c6e01370e84b478d5fa4798cefb8ab |
| 출처 메모 | uspto-grants-2016_04 |