Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-methylpiperidine-4-carboxamide → 1-[6-Chloro-2-(4-fluorophenyl)-4-quinolinyl]-N-methyl-4-piperidinecarboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-methylpiperidine-4-carboxamide | HCID 2760460 | — |
| 반응물 | 4,6-Dichloro-2-(4-fluorophenyl)quinoline | HCID 13603901 | — |
| 용매 | Pyridine water | HCID 66926435 | — |
| 생성물 | 1-[6-Chloro-2-(4-fluorophenyl)-4-quinolinyl]-N-methyl-4-piperidinecarboxamide | HCID 13603927 | — |
반응 단계
The named compound was made in a manner analogous to that of Example 4(c) using 4,6-dichloro-2-(4-fluorophenyl)quinoline, prepared as in Example 20, and N-methylisonipecotamide as starting materials. It was obtained as off-white needles, mp 260°-265° dec on recrystallization from pyridine/water.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04560692 |
| 출처 데이터셋 | uspto-grants-1985_12 |
| ORD ID | ord-99b0e3e06ca044a98979c9cafc1f2c07 |
| 출처 메모 | uspto-grants-1985_12 |