Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Methoxymethyl-oxazole → [2-Amino-6-(4-methoxymethyl-oxazol-2-yl)-3-nitro-pyridin-4-yl]-(6-methyl-pyridin-3-ylmethyl)-carbamic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Methoxymethyl-oxazole | HCID 23080903 | — |
| 반응물 | (2-Amino-6-bromo-3-nitro-pyridin-4-yl)-(6-methyl-pyridin-3-ylmethyl)-carbamic acid ethyl ester | HCID 86614483 | — |
| 촉매 | Bis(triphenylphosphine)palladium chloride | HCID 84124 | — |
| 생성물 | [2-Amino-6-(4-methoxymethyl-oxazol-2-yl)-3-nitro-pyridin-4-yl]-(6-methyl-pyridin-3-ylmethyl)-carbamic acid ethyl ester | HCID 67456273 | — |
반응 단계
The title compound was prepared following the example in preparation 70, using 4-methoxymethyl-oxazole (110 mg), (2-amino-6-bromo-3-nitro-pyridin-4-yl)-(6-methyl-pyridin-3-ylmethyl)-carbamic acid ethyl ester (200 mg) and palladium bis(triphenylphosphine)dichloride (68 mg), giving the product (107 mg) as a yellow gum.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07691877B2 |
| 출처 데이터셋 | uspto-grants-2010_04 |
| ORD ID | ord-9ac59115ac0b469fae32f8dda97f4651 |
| 출처 메모 | uspto-grants-2010_04 |