Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylformamide → 2-Hydroxy-4-methoxybenzoyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 4-Methoxysalicylic Acid | HCID 75231 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 2-Hydroxy-4-methoxybenzoyl chloride | HCID 23118559 | — |
반응 단계
To a solution of 2-hydroxy-4-methoxybenzoic acid (20 g, 118.9 mmol) in 500 mL CH2Cl2 was added thionyl chloride (21.2 g, 178.4 mmol), followed by 0.4 mL DMF. After stirring at rt for 8 h, the reaction mixture was concentrated to a white solid (azeotroped twice from benzene). This material was used as is in the next step.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07691879B2 |
| 출처 데이터셋 | uspto-grants-2010_04 |
| ORD ID | ord-ecf2ec74ab534a90a544406e79f18c91 |
| 출처 메모 | uspto-grants-2010_04 |