Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Amino-3-phenylbutanoic acid → 5-chloro-N-[(1S)-1-cyclohexyl-2-hydroxyethyl]thiophene-2-sulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Amino-3-phenylbutanoic acid | HCID 64808 | — |
| 반응물 | Alloisoleucine, DL- | HCID 99288 | — |
| 반응물 | (alphaS)-alpha-Aminocyclohexaneacetic acid | HCID 736848 | — |
| 반응물 | 5-Bromothiophene-2-sulfonyl chloride | HCID 2733924 | — |
| 반응물 | 5-Chlorothiophene-2-sulfonyl chloride | HCID 2733925 | — |
| 생성물 | 5-chloro-N-[(1S)-1-cyclohexyl-2-hydroxyethyl]thiophene-2-sulfonamide | HCID 12987475 | — |
반응 단계
The following compounds (Examples 12-17, Table 4) were prepared using 5-chlorothiophene-2-sulfonyl chloride, and 5-bromothiophene-2-sulfonyl chloride with L-cyclohexylglycine, β-methyl-DL-phenylalanine, and L-allo-isoleucine and following the procedure outlined in Example 12.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07691884B2 |
| 출처 데이터셋 | uspto-grants-2010_04 |
| ORD ID | ord-6335f1b20dfd47f3bf580483ae39ca30 |
| 출처 메모 | uspto-grants-2010_04 |