Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cyclopropanesulfonyl chloride → Odm-203
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cyclopropanesulfonyl chloride | HCID 2760919 | — |
| 반응물 | N-(2',4'-difluoro-5-(5-(1-methyl-1H-pyrazol-4-yl)-1H-benzo[d]imidazol-1-yl)-biphenyl-3-yl)acetamide | HCID 71554235 | — |
| 생성물 | Odm-203 | HCID 71554322 | — |
반응 단계
The compound was prepared from the compound of Example 1 using the procedures of Example 2 and cyclopropane sulfonyl chloride. 1H NMR (300 MHz, DMSO-d6): δ 10.29 (s, 1H), 8.88 (s, 1H), 8.23 (s, 1H), 8.0 (s, 1H), 7.96 (s, 1H), 7.76-7.64 (m, 3H), 7.6 (s, 2H), 7.5-7.46 (m, 2H), 7.3-7.25 (m, 1H), 3.88 (s, 3H), 2.88-2.85 (m, 1H), 1.02-1.0 (m, 4H); LC-MS (ESI): Calculated mass: 505.54; Observed mass: 506.1 [M+H]+ (rt: 1.517 min).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09447091B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-c8573def410d4e758007e3315e3c7c2a |
| 출처 메모 | uspto-grants-2016_09 |