Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Bromo-3,5-dinitrobenzene → 1-Bromo-3-methoxy-5-nitrobenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Bromo-3,5-dinitrobenzene | HCID 44534 | — |
| 반응물 | Sodium Methoxide | HCID 10942334 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 1-Bromo-3-methoxy-5-nitrobenzene | HCID 12299076 | 65% |
반응 단계
To a solution of 1-bromo-3,5-dinitrobenzene (5 g, 20.2 mmol) in methanol (50 ml) was added sodium methoxide (1.3 g, 24.3 mmol, 1.2 eq.) and the mixture was heated to reflux for 12 h and then quenched with 10% HCl. The solid formed was filtered and dried to afford the compound in 65% yield (3 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09447091B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-ce145fbedab24d23abb7dda07b1d4d0e |
| 출처 메모 | uspto-grants-2016_09 |