Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
tert-Butyl piperazine-1-carboxylate → 1-(3-(Methylsulfonyl)propyl)piperazine dihydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | tert-Butyl piperazine-1-carboxylate | HCID 143452 | — |
| 반응물 | 3-(Methylsulfonyl)propyl methanesulfonate | HCID 10262758 | — |
| 반응물 | N-(2-methoxy-1-methylethyl)-2-piperazin-1-yl-acetamide dihydrochloride | HCID 67245894 | — |
| 생성물 | 1-(3-(Methylsulfonyl)propyl)piperazine dihydrochloride | HCID 49853479 | — |
반응 단계
1-(3-Methanesulfonyl-propyl)-piperazine dihydrochloride was prepared from 1-tert-butyloxycarbonyl-piperazine and methanesulfonic acid 3-methanesulfonyl-propyl ester (prepared according to Baerlocher, F. J. et al. Aust. J. Chem. 1999, 52, 167-172) in an analogous manner as described for the preparation of N-(2-methoxy-1-methyl-ethyl)-2-piperazin-1-yl-acetamide dihydrochloride (example 40).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07705007B2 |
| 출처 데이터셋 | uspto-grants-2010_04 |
| ORD ID | ord-2d00d5a416a84e138dbe3dd3a13d688f |
| 출처 메모 | uspto-grants-2010_04 |