Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine → (2(S)-Pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-(6-thiophen-2-yl-pyridin-3-yl)-methanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine | HCID 853152 | — |
| 반응물 | 6-(Thiophen-2-Yl)Pyridine-3-Carboxylic Acid | HCID 15411144 | — |
| 생성물 | (2(S)-Pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-(6-thiophen-2-yl-pyridin-3-yl)-methanone | HCID 11508383 | — |
반응 단계
The title compound is prepared in a manner substantially analogous to General Procedure D using 6-thiophen-2-yl-nicotinic acid (CAS 179408-54-9) and (S)(+)-1-(2-pyrrolidinylmethyl)pyrrolidine to give the title compound (58 mg). MS (ES+) 342.1 (M+H)+
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07705025B2 |
| 출처 데이터셋 | uspto-grants-2010_04 |
| ORD ID | ord-5b3d7a16dfeb4276b105e2cd2a7d2507 |
| 출처 메모 | uspto-grants-2010_04 |