돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 647586생성일: 2026년 10월 24일

Tryptophol → 1-(Acetamidomethyl)-1-methyl-1,3,4,9-tetrahydropyrano[3,4-b]indole

https://huagongshe.com/ko/reaction/647586

반응식

참여 물질

역할이름HCID투입량
반응물TryptopholHCID 10685—
반응물7-EthyltryptopholHCID 198231—
반응물5-Benzyloxy-3-(2-hydroxyethyl)indoleHCID 744849—
반응물N-[(7-methoxy-1,3,4,9-tetrahydro-1-methylpyrano-[3,4-b]indol-1-yl)methyl]-acetamideHCID 20485044—
반응물N-[(8-ethyl-1,3,4,9-tetrahydro-1-methylpyrano[3,4-b]indol-1-yl)methyl]-acetamideHCID 20485069—
반응물2-(6-Methoxy-1h-indol-3-yl)ethanolHCID 20485101—
반응물N-[(6-phenylmethoxy-1,3,4,9-tetrahydro-1-methylpyrano[3,4-b]indol-1-yl)methyl]-acetamideHCID 20485103—
생성물1-(Acetamidomethyl)-1-methyl-1,3,4,9-tetrahydropyrano[3,4-b]indoleHCID 12708180—

반응 단계

In the same manner but replacing indole-3-ethanol with an equivalent amount of 7-ethylindole-3-ethanol, 6-methoxyindole-3-ethanol or 5-phenylmethoxy-indole-3-ethanol, the following compounds of formula IIa are obtained, respectively: N-[(8-ethyl-1,3,4,9-tetrahydro-1-methylpyrano[3,4-b]indol-1-yl)methyl]-acetamide, N-[(7-methoxy-1,3,4,9-tetrahydro-1-methylpyrano-[3,4-b]indol-1-yl)methyl]-acetamide and N-[(6-phenylmethoxy-1,3,4,9-tetrahydro-1-methylpyrano[3,4-b]indol-1-yl)methyl]-acetamide.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US04409224
출처 데이터셋uspto-grants-1983_10
ORD IDord-cf108d1e3bac41459f0d9bd66c321af4
출처 메모uspto-grants-1983_10