Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Allyl bromide → 5-Allyloxy-2-methylthiopyrimidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Allyl bromide | HCID 7841 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2-(Methylsulfanyl)pyrimidin-5-ol | HCID 588357 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 5-Allyloxy-2-methylthiopyrimidine | HCID 20483481 | — |
반응 단계
4.5 g of 5-hydroxy-2-methylthiopyrimidine, 9.0 g of potassium carbonate and 3.9 g of allyl bromide are together refluxed in 50 ml of acetone, with stirring, for 41/2 hours. The inorganic salts are removed by filtration, and the filtrate is concentrated under reduced pressure. The oil remaining yields, from petroleum ether, 5-allyloxy-2-methylthiopyrimidine, m.p. 41°-42°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04410530 |
| 출처 데이터셋 | uspto-grants-1983_10 |
| ORD ID | ord-22464af4a91e4835a364c5380e760b20 |
| 출처 메모 | uspto-grants-1983_10 |