Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HCID 19936753, 화합물 → 2-n-butyl-1-(2-chloro-6-fluorophenyl)methyl-1H-imidazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | HCID 19936753 | HCID 19936753 | — |
| 반응물 | N-[2-{1 [(2-chlorophenyl)methyl]-2-n-butyl-1H-imidazol-5-yl}ethyl]phenylalanine | HCID 54198642 | — |
| 생성물 | 2-n-butyl-1-(2-chloro-6-fluorophenyl)methyl-1H-imidazole | HCID 19936774 | — |
반응 단계
The procedures of Example 1(ii iii) were used. From 7.63 g of crude 2-n-butyl-1-(2-chloro-6-fluorophenyl)methyl-1H-imidazole was obtained 2.8 q of 2-n-butyl-1-(2-chloro-6-fluorophenyl)methyl-5-hydroxymethyl-1H-imidazo le; mp 106°-108° C. (from ethyl acetate). This material was oxidized with manganese dioxide and worked up as described to give 0.88 g (63%) of 2-n butyl-2-(2-chloro-6-fluorophenyl)methyl-1H-imidazol-5-carboxaldehyde; mp 88°-90° C. (from ethyl acetate).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05248689 |
| 출처 데이터셋 | uspto-grants-1993_09 |
| ORD ID | ord-d2c9533997c74d79a948283e529ded3f |
| 출처 메모 | uspto-grants-1993_09 |